Dr. Kapur is an Associate Professor in the Department of Medicine and Division of Cardiology. He is the Executive Director of the CardioVascular Center for Research and Innovation (CVCRI), Executive Director of the Cardiogenic Shock Working Group, Director of the Acute Circulatory Support Program, Director of the Interventional Research Laboratory, and Director of the Cardiac Biology Research Center (CBRC) at Tufts Medical Center. He is a dual, board-certified Interventional Cardiologist and Advanced Heart Failure/Cardiac Transplant specialist. His clinical expertise focuses on invasive hemodynamics, mechanical circulatory support devices, complex percutaneous coronary intervention, and interventional therapies for patients with heart failure. He serves as Principal Investigator for several multicenter trials in mechanical circulatory support including the STEMI-Door-to-Unload Trial. His research expertise focuses on molecular mechanisms of cardiac remodeling and myocardial recovery. His laboratory was the first to identify that acute mechanical unloading of the left ventricle activates a cardioprotective signaling program in the setting of acute myocardial infarction and was the first to identify novel molecular mechanisms regulating biventricular function with extracorporeal membrane oxygenation. His laboratory was also the first to establish a functional role for the transforming growth factor beta co-receptor endoglin in cardiac remodeling due to heart failure. Dr. Kapur developed the pulmonary artery pulsatility index, a widely used measure of right heart failure and is the inventor on multiple patents focused on device and drug therapy development. He co-founded and served as head of the scientific advisory board for preCARDIA, an award-winning device-based company focused on cardio-renal unloading for heart failure. Dr. Kapur has mentored multiple pre- and post-doctoral national and international trainees and directs a program for junior faculty development. He also developed the first combined Interventional Heart Failure Clinical Fellowship program with alumni across the United States.
Navin K. Kapur, MD