Dr. Gutierrez is the Marie S. Ingalls Endowed Chair in Nephrology Leadership, Professor of Medicine, and Director of the Division of Nephrology at the University of Alabama at Birmingham (UAB). He is also the director and PI of the Center for Clinical and Translational Science, the CTSA hub…
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Dr. Gutierrez is the Marie S. Ingalls Endowed Chair in Nephrology Leadership, Professor of Medicine, and Director of the Division of Nephrology at the University of Alabama at Birmingham (UAB). He is also the director and PI of the Center for Clinical and Translational Science, the CTSA hub at UAB, senior associate dean for clinical and translational research in the Heersink School of Medicine, and associate vice president of medicine and biomedical research at UAB. His group’s research efforts are concentrated in three major areas. First, he has made critical contributions in delineating the relationships between disturbances in mineral metabolism and clinical outcomes, with a special interest in behavioral and environmental exposures that may modulate these pathways. Within this area of interest, he has primarily focused on the connections between disturbances in phosphorus metabolism and cardio- and cerebrovascular morbidity and mortality, including the emerging role of fibroblast growth factor 23 (FGF23). Second, he has examined the role of nutrition in the development and progression of metabolic complications related to kidney injury, focusing on the role of phosphorus and sodium-based food additives in the pathophysiology of inflammation, insulin resistance and endothelial dysfunction in individuals from across the spectrum of kidney function. Third, he has investigated the association of blood and urine biomarkers of kidney tubular injury with kidney and cardiovascular outcomes. A consistent thread weaving through Dr. Gutiérrez’s research is a focus on finding potentially modifiable risk factors for chronic disease, particularly kidney disease and stroke. His group has made original and important contributions to this field, and it continues to investigate these issues through a combination of epidemiological, patient-oriented and genetic approaches.
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