Matthew Steinhauser was an undergraduate and medical student at the University of Michigan, where he received research training focused on cytokine signaling pathways underpinning acute inflammatory responses in the laboratory of Steven Kunkel. After a residency and chief residency in internal medicine at Columbia University Medical Center, he moved to the Brigham and Women’s Hospital in 2006 and completed a clinical cardiology fellowship and research training in stem cell biology and heart regeneration in the laboratory of Richard Lee. In 2013, Dr. Steinhauser established his laboratory in the Division of Genetics at Brigham and Women’s Hospital, shifting his research focus to adipose tissue biology and metabolism. His lab has focused on three inter-related areas: (1) the development and human translation of a new imaging method called multi-isotope imaging mass spectrometry for studying metabolism at sub-organelle resolution; (2) establishment of an age dependent decline in adipose tissue plasticity as a driver of systemic insulin resistance, including elucidation of the molecular circuity underpinning the quiescence of adipocyte precursor cells; and (3) advancement of our understanding of the metabolic adaptation to fasting in humans. In 2019, Dr. Steinhauser moved his lab to the University of Pittsburgh Aging Institute where he is Director of the Center for Human Integrative Physiology.