Dr. Denburg’s research focuses on bone and mineral metabolism in childhood kidney diseases, including chronic kidney disease (CKD), glomerular disease, and urinary stone disease. In particular, she has pursued translational work in vitamin D-mediated innate immunity in nephrotic patients and ancillary studies of vitamin D metabolism and vitamin D-binding protein in pediatric patients with CKD. She is completing an ancillary study to the Nephrotic Syndrome Study Network (NEPTUNE), to relate baseline measures of vitamin D-related mineral metabolism to tubulointerstitial injury, and a pilot trial of vitamin D supplementation in patients with glomerular disease. She is a co-investigator in phase two of the NephCure Kidney Network, a PCORI-funded patient-powered research network focused on glomerular disease. Her collaborative studies have focused on vitamin D metabolism and bone structure in children with CKD, nephrotic syndrome, and inflammatory bowel disease.
Michelle R. Denburg, MD, MSCE