Dr. Locke is an abdominal transplant surgeon specializing in innovative strategies for the transplantation of incompatible organs, disparities in access to and outcomes after solid organ transplantation, and transplantation of HIV-infected end-stage patients. Dr. Locke completed an undergraduate degree in biology and chemistry at Duke University and her medical degree at East Carolina University prior to matriculating to Johns Hopkins Hospital where she received training in general surgery and multi-visceral abdominal transplantation. Dr. Locke completed her Master of Public Health degree with an emphasis in biostatistics and epidemiology at the Johns Hopkins Bloomberg School of Public Health.

Her research interests include complex statistical analysis and modeling of transplant outcomes and behavioral research focused on health disparities. She has authored more than 140 articles in peer-reviewed journals and 20 book chapters, and is an NIH R01-funded investigator. Dr. Locke is a Deputy Editor for the American Journal of Transplantation, and is an editorial board member for Annals of Surgery. She is a member of the American Society of Transplantation (AST), American Society of Transplant Surgeons (Councilor-at-Large), and American Society of Nephrology, as well as, a Fellow of the American College of Surgeons (ACS), Society of University Surgeons (Councilor-at-Large), the Southern Surgical Association, Society of Clinical Surgery, and the American Surgical Association. Dr. Locke is the recipient of numerous honors including the 2016 James IV Association of Surgeons Traveling Fellow, ACS Traveling Fellow 2018, Association for Clinical & Translational Science (ACTS) Distinguished Investigator Award: Translation into Public Benefit and Policy (2018), and the AST Clinical Science Faculty Award 2020.

Dr. Locke is currently tenured Professor of Surgery and the Arnold G. Diethelm Endowed Chair in Transplantation Surgery at the University of Alabama at Birmingham, and serves as Director of the Comprehensive Transplant Institute and Chief of the Division of Abdominal Transplant Surgery.