Rajat Deo, MD, MTR, is an Associate Professor of Medicine and Director of the Penn Arrhythmia Genetics Program at the University of Pennsylvania Perelman School of Medicine. Dr. Deo has expertise in cardiovascular risk stratification especially as it relates to sudden cardiac death (SCD) and fatal cardiovascular disease. He has helped design adjudication protocols for sudden cardiac death in several large NIH cohort studies. In addition, he has devoted his research efforts to large-scale proteomics underlying the development of cardiovascular diseases and associated sub-phenotypes. Dr. Deo has developed proteomic risk models for predicting incident and secondary cardiovascular events in different populations. These risk models have outperformed traditional clinical scores. In addition, he has integrated genetic and proteomic measures to gain biologic insights into proteins and pathways that are in the causal pathway for cardiovascular disease. Dr. Deo is also using high-dimensional data reduction methods and AI to evaluate repeated ECG measures and continuous cardiac telemetry. His goal has been to identify subtle ECG changes across time that correlate with and are predictive of arrhythmia onset. 

A graduate of the Massachusetts Institute of Technology, he attended medical school at the University of Michigan. He completed his internship and residency at the University of Texas Southwestern Medical Center. He then completed a general cardiology fellowship at the University of California, San Francisco and an electrophysiology fellowship at the Johns Hopkins Hospital. Upon starting his faculty position, he completed a Masters of Science in Translational Research at the University of Pennsylvania.