Resources:
Email: john.floras@sinaihealth.ca
Phone: None available.
Dr. Floras is Professor of Medicine at the University of Toronto, Mount Sinai Hospital’s Deputy Physician-in-Chief for Research, and University Health Network-Sinai Health Division of Cardiology Research Director.
His MD (Toronto) was followed by doctoral and post-doctoral research concerning the neural regulation of blood pressure in health and disease in Oxford and Iowa City and clinical training in Toronto. He established, in 1985, the first Canadian human microneurographic-cardiovascular laboratory.
For over 4 decades, with support from the Heart and Stroke Foundation and Canadian Institutes of Health Research, he has investigated via mechanistic studies, physiological perturbations, and multi-national clinical trials, human circulatory and cardiac control mechanisms in human health and disease, with particular emphasis on the role of the autonomic nervous system, peptides, and sleep-related breathing disorders in the autonomic disequilibrium of heart failure. His findings, which have informed clinical guidelines and drug and device development, appear in > 270 original contributions, with an h index of 92 and >36K citations. He co-edited ‘Sleep Apnea: Implications for Cardiovascular and Cerebrovascular Disease’, the first text on this topic.
He has received a Rhodes Scholarship, the Royal College of Physicians Medal in Medicine, the CIHR Institute of Circulatory and Respiratory Health Prize in Cardiovascular Sciences, the Canadian Cardiovascular Society Research Achievement Award, and Hypertension Canada’s Senior Investigator Award. In 2020 he delivered the AHA Council on Hypertension Corcoran Lecture and in 2021 the APS’s Ludwig Lecture. From 2004-2018, he held the Canada Research Chair in Integrative Cardiovascular Biology.
He has devoted substantial time towards early career professional development, intra-Departmentally; as President of the Canadian Hypertension Society, and thereafter steward of its training endowment; as Chair of the Banting Research Foundation, Canada’s oldest medical research granting agency, which now funds high-risk proposals from new faculty; and as a Schmidt Science Fellow final selection panelist.