Timothy A. Chan, MD, PhD
Photo: Timothy A. Chan



Elected 2013

Timothy A. Chan MD, PhD is a physician scientist, Staff, Professor, and attending physician at the Cleveland Clinic and the Case Comprehensive Cancer Center. He is PI of a cancer genetics laboratory and is an expert in cancer biology and immunogenomics.  Dr. Chan is Chair and Director of the Center for Immunotherapy and Precision Immuno-Oncology at the Cleveland Clinic, which focuses on immunotherapy research and developmental therapeutics.  He is co-director of the National Center for Regenerative Medicine and director of the Case Comprehensive Cancer Center Immuno-Oncology Program.  Dr. Chan received an MD, a PhD in cancer genetics, completed a residency in radiation oncology, and finished a fellowship at the Johns Hopkins School of Medicine. The Chan laboratory specializes in using genomic analysis to characterize the drivers of genetic programs underlying immunotherapy and oncogenesis. These approaches include large-scale analyses, functional genomics, immunogenomics, biochemical and molecular analyses, and mouse modeling. The lab has a special interest in deciphering the mechanisms underlying immunotherapy treatment response, resistance, and mechanisms. He is an integral part of the clinical teams at the Cleveland Clinic.  Dr. Chan was previously at the Memorial Sloan Kettering for over a decade where he was the Paine Webber Chair in Cancer Genetics, a tenured Professor, Director of the Immunogenomics Program, and Vice Chair of the Dept. of Radiation Oncology.  He has over 250 publications in journals including Nature, Science, The New England Journal of Medicine, Cell, and others.  He is on the scientific advisory board for Cell and the Frederick National Laboratory/National Cancer Institute.  He is an NCI Outstanding Investigator and an elected member of the American Association of Physicians (AAP).

Honors / awards

National Academy of Medicine (2023)