Dr. Peter A. Noseworthy is a Professor of Medicine at Mayo Clinic, Chair of the Division of Cardiac Electrophysiology, and President of the Mayo Clinic Foundation for Medical Education and Research. A practicing cardiac electrophysiologist, he specializes in catheter ablation of complex arrhythmias, including atrial fibrillation and ventricular tachycardia.

Dr. Noseworthy leads an internationally recognized research program focused on improving outcomes for patients with heart rhythm disorders. His work spans clinical trials, comparative effectiveness research, and AI-enabled diagnostics, informed by his expertise in complex ablation. He has authored more than 400 peer-reviewed publications in leading journals, including The Lancet and Nature Medicine, and holds an h-index exceeding 80. His research has been continuously supported by the NIH, AHRQ, FDA, and industry, and he is an inventor on eight U.S. patents, including foundational technologies in artificial intelligence–enabled electrocardiography (AI-ECG).

His contributions to AI-ECG are among his most influential. He co-developed algorithms that detect atrial fibrillation during sinus rhythm and identify patients with reduced ejection fraction using routine ECGs. Validated in large prospective studies, these tools have been integrated into clinical care, shaping both policy and practice while demonstrating how AI can be scaled across health systems to improve screening and risk stratification.

Dr. Noseworthy has also advanced pragmatic trial methodology, leading large decentralized studies that leverage real-world data, remote monitoring, and AI-enabled interventions, particularly to improve inclusion of underrepresented populations.

Beyond his scientific contributions, he has served in key national leadership roles, including chairing the American Heart Association Scientific Statement on Subclinical Atrial Fibrillation, contributing to the 2023 AHA/ACC Guidelines, and leading the Heart Rhythm Society’s digital health committee. A dedicated mentor, he has trained numerous fellows and scholars, many of whom now hold independent funding and leadership positions.